SiDMAP technology, with the use of specifically chosen 13C or 2H labeled substrates, provides information regarding optimality/homeostasis of a biological System. SiDMAP is the metabolic optimality and adaptation interpretation tool for research, biology and medicine.
SiDMAP is able to capture the overall system-effect of diseases, drugs, age, individual variations, among other perturbations. This is by determining associations among cell compartment enzyme reactions over time, drug dosing or altering the substrate environment.
SiDMAP measures metabolic adaptation to perturbations in a sensitive, specific, quantitative, real time and validated manner.
SiDMAP has been successfully validated in a vast array of human diseases, a non-exclusive list is provided below:
SiDMAP applications determine optimality in biological systems as the end result of the inner working of the metabolic/signaling/genetic compartments and their interactions with the environment. This is commonly known as homeostasis, which is characterized by a certain pattern of associations among biochemical reaction pathways that SiDMAP reveals.