Wai-Nang Paul Lee, M.D.

Scientific Co-Advisor

Dr. Lee is currently a Professor of Pediatrics at UCLA and former Division Chief of Pediatric Endocrinology, the Director of the Stable Isotope Research Laboratory at Harbor-UCLA Medical Center and Sidmap.

After graduating from the University of California, Berkeley with a bachelors degree in Biochemistry in 1966, Dr. Lee went on to study medicine at Stanford University, and ultimately completed his pediatric internship and residency at Cleveland Metropolitan General Hospital and USC-LAC Medical Center in Los Angeles, respectively. In 1976, he completed a two-year Fellowship in Pediatric Endocrinology at UCLA and became an Assistant Professor of Pediatrics at the University. In 1982, he received his MBA with honors from California State University, Northridge.

Dr. Lee received his initial training in mass spectrometry in 1978, from Dr. Daniel Knapp during a NIH NCRR fellowship.  Dr. Lee is a pioneer in developing the use of the least squares approach to the quantitation of stable isotopes in mass spectrometry.  The method was later adopted for mass isotopomer distribution analysis.  In collaboration with Dr. Joseph Katz who was a pioneer in the application of tracers in metabolic studies, Dr. Lee published extensively on the use of mass and positional mass isotopomer to trace metabolic pathways, which has evolved into the field of metabolomics as we know it today.  From 1993-1996, Dr. Lee was a member of the Metabolism Study Section of the Scientific Review Branch of the NIH.  Dr. Lee has received numerous research and fellowship training grants, has published many seminal articles on the use of stable isotopes in metabolic research.  Dr. Lee has been the Director of Stable Isotope Research Laboratory since 1986. His laboratory currently utilizes Agilent GC/MS, ABI5000 LC/MS/MS and LCQdeca for metabolite analysis. Through his research, Dr. Lee has gained unique understanding of cellular metabolism especially in the area of determining metabolic phenotypes in cells.  Dr. Lee continues to serve on many committees within the Harbor-UCLA Medical Center community. He is Board Certified by the American Board of Pediatrics and regarded as an expert in the field of Pediatric Endocrinology and Diabetes.

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